The chili pepper, from an evolutionary perspective, is the tomato’s long-lost spitfire cousin. They split off from a common ancestor 19 million years ago but still share some of the same DNA. While the tomato plant went on to have a fleshy, nutrient-rich fruit yielding bountiful harvests, the more agriculturally difficult chili plant went defensive, developing capsaicinoids, the molecules that give peppers their spiciness, to ward off predators.
With the latest gene-editing techniques, it could be possible, although challenging, to make a tomato produce capsaicinoids as well, researchers argue in an opinion article publishing January 7 in the journal Trends in Plant Science. Their objective isn’t to start a hot, new culinary fad—although that’s not completely off the table—but to have an easier means of mass producing large quantities of capsaicinoids for commercial purposes. The molecules have nutritional and antibiotic properties and are used in painkillers and pepper spray.
The spicy taste that capsaicinoids add isn’t a taste, but a reaction to pain. They activate nerve cells in the tongue that deal with heat-induced pain, which the brain interprets as a burning sensation. Evidence suggests that the evolution of capsaicinoids helped chili peppers deter small mammals from eating their fruit. Birds, which are much better seed dispersers, show no pain response to the molecules.
There are at least 23 different types of capsaicinoids, which originate from the pith of the chili pepper. The spiciness of a pepper is determined by the genes that regulate capsaicinoid production, and less pungent peppers have mutations affecting this process. Previous gene sequencing work has shown that tomatoes have the genes necessary for capsaicinoids but don’t have the machinery to turn them on.
The sequencing of the chili pepper genome and the discovery that the tomato has the genes necessary for pungency paves the way for engineering a spicy tomato. The researchers write that not only will this endeavour help better understand the evolution of this unique botanical trait and allow for the development of tomato capsaicinoid biofactories, but perhaps allow for the development of some new varieties of produce in the grocery aisle.
Rezende-Naves et al. 2019 “Capsaicinoids: pungency beyond Capsicum” Trends in Plant Science, DOI: 10.1016/j.tplants.2018.11.001