European studies disprove Seralini’s GM maize claims

Three studies of G-TwYST launched by European authorities disprove the controversial study on genetically modified (GM) maize by Gilles-Éric Séralini.

In September 2012, Séralini, a professor at the University of Caen, published a sensational article in Food and Chemical Toxicology, which later retracted the study, claiming that GM maize NK603 induces tumors in rats. The results of the European Union funded G-TwYST project were reported on April 29, 2018 at a conference in Bratislava, Slovakia which confirms the lack of health effects of maize  NK603 in the 90-day rat feeding studies. These studies conclude that:

No potential risk for humans and animals was identified in the original assessment of the GM maize NK603. In particular, no triggers for animal feeding studies were identified from the molecular characterization and the compositional, phenotypic and/or agronomic analyses of NK603. The G-TwYST data from 90-day and long-term rodent feeding studies did not identify potential risks as well, and therefore support the results from the initial analyses.
The G-TwYST data from the long-term feeding rat study with NK603 did not identify potential risks as well, and therefore support the results from the initial analyses and 90-day rat feeding studies.
Three immune function assays not included in the OECD Test Guideline 408 for single substances were performed in the course of the two 90-day rat feeding trials with the GM maize NK603. The GM maize NK603 did not affect the immune functions tested in studies.

The necessity to perform a feeding trial with whole food/feed should be carefully evaluated given the high number of animals needed (in the case of the G-TwYST project: 720, 172 and 268 in the performed three rat feeding studies).

According to the French Association of Plant Biotechnology (AFBV) the results of these experiments are now published by While referring to G-TwYST one-year and two-year long-term studies, AFBV states that “the results do not show any toxic effects of the corn analyzed and provide nothing more than 90-day studies as predicted by toxicologists”. The AFBV declares that these studies “refute the main conclusions drawn from the GE Seralini studies on the toxicity of the analyzed GMO maize as no potential risk has been identified. In addition, these new studies contradict Seralini’s proposal on the need to carry out long-term studies.”

The results from G-TwYST
Source: Crop Biotech Update

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